Upon its publication by the MIT Press in 1972, Learning from Las Vegas was immediately influential and controversial. The authors made an argument that was revolutionary for its time—that the billboards and casinos of Las Vegas were worthy of architectural attention—and offered a challenge for contemporary architects obsessed with the heroic and monumental. The physical book itself, designed by MIT's iconic designer Muriel Cooper, was hailed as a masterpiece of modernist design, but the book's design struck the authors as too monumental for a text that praised the ugly and ordinary over the heroic and monumental. The MIT Press published a revised version in 1977—a modest paperback that the authors felt was more in keeping with the argument of the book—and the original Cooper-designed book fell out of print and became a highly sought-after collectors' item; it now sells for thousands of dollars in the rare book market, while the author-redesigned paperback has remained continuously in print at a price affordable to students. Now, decades after the original hardcover edition sold out, the MIT Press is publishing a facsimile edition of the original large-format Cooper-designed edition of Learning from Las Vegas, complete with translucent glassine wrap. This edition also features a spirited preface by Denise Scott Brown, looking back on the creation of the book and explaining her and Robert Venturi's reservations about the original design.

Learning from Las Vegas begins with the Las Vegas Strip and proceeds to "Ugly and Ordinary Architecture, or the Decorated Shed," on symbolism in architecture and the iconography of urban sprawl. As Scott Brown says in her introduction, the book “upended sacred cows … would not bad-mouth bad taste, and redefined architectural research.”